What are the statin risk categories?

Publish date: 2023-05-29
Three major high-risk categories for adults are severe hypercholesterolemia, diabetes, and ages 40 to 75 years. For patients with severe hypercholesterolemia (LDL-C levels ≥190 mg/dL [4.9 mmol/L]), begin immediate statin therapy.

Furthermore, what are the 4 statin benefit groups?

Since the 2013 update, the American College of Cardiology/American Heart Association guidelines for the management of blood cholesterol have identified 4 statin benefit groups: clinical ASCVD, severe hypercholesterolemia (low-density lipoprotein cholesterol [LDL-C] ≥190 mg/dL), diabetes mellitus in adults, and those

Furthermore, which of the following patients is a candidate for statins? The USPSTF concludes that adults who smoke or have dyslipidemia, diabetes, or hypertension and a 10% or greater 10-year CVD event risk should be offered a low- to moderate-dose statin. Adults with diabetes or dyslipidemia and a 20% or greater 10-year CVD event risk are most likely to benefit from statin use.

Correspondingly, what are the high intensity statins?

Definition of statin intensity was based on the guideline from ACC/AHA. Atorvastatin 40 or 80 mg and rosuvastatin 20 mg were defined as high-intensity statins, and the other statins were classified as non-high-intensity statins.

What is the best cholesterol medication with the least side effects?

In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications.

Who gets a statin?

Young Adults (20-39 Years of Age) Along with lifestyle changes, young adults with primary elevations of LDL-C 190 mg/dL or greater may take statins. Stress to young adults that prolonged hyperlipidemia before age 55 increases their risk of coronary heart disease significantly.

Which is best statin?

For people who need a high-intensity statin: ¦ generic atorvastatin 40 mg or 80 mg All of our Best Buys—atorvastatin, lovastatin, pravastatin, and simvastatin—have been shown to reduce the risk of heart attack and deaths from heart attacks, and are available as inexpensive generics.

Who should be on high intensity statin?

In patients with primary hypercholesterolemia who have LDL cholesterol levels ≥ 190 mg/dL, physicians should start with a high-intensity statin without calculating the 10-year risk of ASCVD (class I). If the LDL cholesterol level remains 100 mg/dL or higher, add ezetimibe (class IIa).

Do statins cause kidney problems?

High-Dose Statins Linked to Acute Kidney Damage. TUESDAY, March 19 (HealthDay News) -- People who take high doses of popular cholesterol-lowering drugs called statins may be more likely to develop kidney problems, a new study suggests.

When should a statin patient be started?

The U.S. Preventive Services Task Force recommends starting low- to moderate-dose statins in adults ages 40 to 75 who have one or more risk factors for cardiovascular disease (CVD) and at least a 1 in 10 chance of having a CVD event in the next 10 years.

What does dyslipidemia mean?

Dyslipidemia is an abnormal amount of lipids (e.g. triglycerides, cholesterol and/or fat phospholipids) in the blood. In developed countries, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood. This is often due to diet and lifestyle.

How do statins work?

Statins, and How Statins Work Statins have been clearly shown to reduce blood cholesterol and prevent atherosclerosis, or heart disease. They work by reducing the liver's production of cholesterol. They block an enzyme called HMG CoA Reductase that the liver uses to make cholesterol.

What are the new cholesterol guidelines?

Based on the newest research, experts now believe that lowering “bad” cholesterol—known as low-density lipoprotein (LDL) cholesterol—to levels less than 70 milligrams per deciliter in high risk patients is best for reducing heart disease complications and risk of dying.

What is a healthy cholesterol level by age?

Cholesterol levels for adults Total cholesterol levels less than 200 milligrams per deciliter (mg/dL) are considered desirable for adults. A reading between 200 and 239 mg/dL is considered borderline high and a reading of 240 mg/dL and above is considered high. LDL cholesterol levels should be less than 100 mg/dL.

Is atorvastatin a high intensity statin?

High-intensity statin therapies are atorvastatin (40–80 mg) or rosuvastatin (Crestor; 20–40 mg). Moderate-intensity statin therapies include atorvastatin (10–20 mg), rosuvastatin (5–10 mg), simvastatin (20–40 mg), pravastatin (40–80 mg), and several others.

What is statin intensity?

Table 1Statin Dosing and ACC/AHA Classification of Intensity
StatinDosage
Low-intensity (LDL-C reduction <30%)Moderate-intensity (LDL-C reduction 30% to <50%)
Pitavastatin1 mg2 to 4 mg
Pravastatin10 to 20 mg40 to 80 mg
RosuvastatinNA5 to 10 mg

What is a high intensity workout?

HIIT, or high-intensity interval training, is a training technique in which you give all-out, one hundred percent effort through quick, intense bursts of exercise, followed by short, sometimes active, recovery periods. This type of training gets and keeps your heart rate up and burns more fat in less time.

Do Statins lower triglycerides?

High doses of a strong statin (simvastatin, atorvastatin, rosuvastatin) lower triglycerides, by as much as approximately 50%, and raise high-density lipoprotein (HDL) cholesterol. The greater the baseline level of triglycerides the greater the percent triglyceride reduction will be with statin treatment.

When should I start rechecking cholesterol after starting statins?

Liver transaminase levels should be checked before starting statins; guidelines vary on if and when to recheck them in the absence of symptoms. Lipid levels should be rechecked one to three months after starting statins, although guidelines differ on subsequent checks.

Is 40 mg simvastatin high?

Based on the results of a controlled clinical study, the recommended starting dosage is simvastatin 40 mg/day in the evening. The usual dose of simvastatin is 20 to 40 mg/day given as a single dose in the evening in patients at high risk of coronary heart disease (CHD, with or without hyperlipidaemia).

When should I stop statin therapy?

It found that older adults who stopped taking statins had a higher chance of developing heart or blood vessel problems. Some experts point to this as support for continued use of statin therapy after age 75, but others advise caution. Help Healthline make the world stronger and healthier.

What are the doses of statins?

High doses -- also called high-intensity statin therapy -- included 40 to 80 milligrams (mg) of atorvastatin (Lipitor) or 20 to 40 mg of rosuvastatin (Crestor) daily. Examples of moderate doses include 10 to 20 mg of Lipitor and 5 to 10 mg of Crestor, the study reported.

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